Everything from banking to government services, from shopping to gambling has moved on-line in the past decade, yielding huge efficiency gains for suppliers and (for the most part) an improved experience for the customer. Suppliers that have failed to adjust
Total Scientific Blog
The earliest biomarkers, such a body temperature or blood pressure, were single measurements that reflected multiple physiological processes. Today, though, our reductionist approach to biology has turned up the resolution of our lens: we can measure levels of individual proteins,
On May 7th 2012, Roche terminated the entire dal-HEART phase III programme looking at the effects of their CETP inhibitor dalcetrapib in patients with acute coronary syndrome. The immediate cause was the report from the data management committee of the
The interleukins are an odd family. One name encompasses dozens of secreted proteins that are linked by function rather than by structure. And even that common function is very broadly defined: cytokines that communicate between cells of the immune system. Defined
They are everywhere: so called ‘present organic pollutants’, or POPs for short. Since almost all the everyday items that make modern life so much easier emerged from a chemical factory, its not surprising that environmental contamination with organic chemicals is
If a test with prognostic value exists, should it be used for population screening? On the face of it, it’s a simple question, but it doesn’t have a simple answer. Like most things in life, it depends on the context:
Personalized Medicine Demands Investment in Innovative Diagnostics: Will the Returns be High Enough?
Several very senior pharma executives were recently overhead by a journalist discussing what each of them viewed as the most important changes in the way healthcare will be delivered over the coming decade. Each of them listed several such factors,
Obtaining rapid and reliable diagnosis of infectious diseases is usually limited by the sensitivity of the detection technology. Even in severe sepsis, accompanied by organ failure and admission to an intensive care unit, the causative organism is often present at
A wide-ranging study pre-published on-line in Nature last month points the finger at the chemokine CCL2 (also known as MCP-1, or JE in mice) as a key regulator of tumour metastasis. Intriguingly, CCL2 seems to participate in the
- 1
- 2